Nup98 FG domains from diverse species spontaneously phase-separate into particles with nuclear pore-like permselectivity
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چکیده
منابع مشابه
Nup98 FG domains from diverse species spontaneously phase-separate into particles with nuclear pore-like permselectivity
Nuclear pore complexes (NPCs) conduct massive transport mediated by shuttling nuclear transport receptors (NTRs), while keeping nuclear and cytoplasmic contents separated. The NPC barrier in Xenopus relies primarily on the intrinsically disordered FG domain of Nup98. We now observed that Nup98 FG domains of mammals, lancelets, insects, nematodes, fungi, plants, amoebas, ciliates, and excavates ...
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ژورنال
عنوان ژورنال: eLife
سال: 2015
ISSN: 2050-084X
DOI: 10.7554/elife.04251